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Overview

Nucleotrace PITTs offer many advantages over other DNA and non-DNA based tracing technologies. PITTs are covered by multiple patent families. 

Advantages of Nucleotrace technology over competitors
Why Nucleotrace?

Why is Nucleotrace different to other DNA tracing technologies?

 

Nucleotrace uses fundamentally different chemistry, different DNA-encoding approaches, and nanopore sequencing to offer a step change in DNA tracing.

  • Product-integrated and surface labelling. PITTs tag may be integrated into powders and liquids or applied to surfaces.

  • No specialist expertise required. Instrument-free sample preparation requires similar expertise as a RAT test.

  • Rapid CPU sample processing. Our soft-decision DNA encoding system permits rapid real-time sample analysis using CPU processing only (not GPU). Up to eight samples can be decoded in parallel on a laptop in 20 seconds.

  • Field compatible. Labelling, sampling, and testing may be carried out in the field.

  • CBNRE compatible. Our labelling formulations stabilise the encoded PITTs against Chemical, Biological, Nuclear, Radiological, and Explosive (CBNRE) conditions. ​​This includes resistance to:

    • Temperature: transient exposure to 2,500oC or ​four hours at 150oC

    • pH: range of pH 1-13

    • Radiation: tested to 15 kGy gamma irradiation

    • Chemical attack: resistant to most chemicals

    • Biological attack: all DNases

  • Tier 4 tracing capability. Nucleotrace is the only Tier 4 tracing technology. This means that we can identify any subset of labelled materials in a pool of two or more labelled materials in the same sample, for multiple samples simultaneously.

Nucleotrace is the only Tier 4 tracing technology that enable the rapid identification of multiple ingredients in a product
Why DNA?

Why are PITTs DNA-based?

 

Unlike other information storage media DNA is safe and may be added to consumable products, including pharmaceuticals.

Additionally, DNA will always be relevant because all life on Earth is DNA-based. This provides a strong incentive to continue to improve DNA synthesis and sequencing technologies. Twenty years ago it cost more than $1 billion to sequence the human genome - today it is less than $1,000 and performed on a smartphone-size USD device. Nucleotrace will continue to leverage these advances and only get better.

Why not spectral?

What advantages do PITTs offer over spectral technologies?

 

​Spectral identifiers can only be used to label surfaces and cannot be mixed. In contrast, DNA is:

  • Suitable for surface and product-integrated labelling

  • Non-toxic and may be used to label consumable products and pharmaceuticals

  • Decodable when two or more tags/identifiers are mixed together

  • Detectable when transferred onto another object/material

  • Compatible with signal-to-noise based forensic sample analysis

These key differences open up a much wider range of use cases for DNA-based tracing systems.

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